The Ohio House is set to vote on a bill banning abortions based on a diagnosis of Down syndrome.
The bill being considered Wednesday would subject doctors who perform abortions in such cases to criminal penalties and the potential loss of their medical licenses.
If approved by the House, the bill would still need approval in the Senate before going to Gov. John Kasich for his potential signature.
The bill could make Ohio the third state to approve such a ban on abortions. A similar but wider-reaching law in Indiana was recently struck down by a federal court.
Also Wednesday, House hearings begin again on the so-called "Heartbeat Bill" that would ban abortions at the first detectable fetal heartbeat.
Advocates want the bill to spark a legal challenge to Roe v. Wade, the landmark U.S. Supreme Court decision that legalized abortion.
The second bill's proponents describe terminating pregnancies in such cases as a form of discrimination stemming for misinformation and society's growing perfectionism.
Abortion rights groups say it's part of a steady effort in Ohio to limit legal abortions.