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	<title>WOSU News &#187; genetic</title>
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		<title>WOSU News &#187; genetic</title>
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		<title>Ohio’s Newborn Screening Program Could Help Prevent Disorders</title>
		<link>http://wosu.org/2012/news/2012/05/11/ohio%e2%80%99s-newborn-screening-program-could-help-prevent-disorders/</link>
		<comments>http://wosu.org/2012/news/2012/05/11/ohio%e2%80%99s-newborn-screening-program-could-help-prevent-disorders/#comments</comments>
		<pubDate>Fri, 11 May 2012 11:19:15 +0000</pubDate>
		<dc:creator>WOSU News Staff</dc:creator>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Newsletter Stories]]></category>
		<category><![CDATA[blood]]></category>
		<category><![CDATA[disease]]></category>
		<category><![CDATA[disorder]]></category>
		<category><![CDATA[doctors]]></category>
		<category><![CDATA[genetic]]></category>
		<category><![CDATA[public health]]></category>
		<category><![CDATA[treatment]]></category>

		<guid isPermaLink="false">http://wosu.org/2012/news/?p=28109</guid>
		<description><![CDATA[There’s one thing all Americans share at birth. It's the experience of having a heel stick, a jab that draws blood used for all types of screening. How much can doctors learn from a few drops of blood squeezed from the heel?]]></description>
				<content:encoded><![CDATA[<p>There’s one thing all Americans share at birth. It&#8217;s the experience of having a heel stick, a jab that draws blood used for all types of screening. How much can doctors learn from a few drops of blood squeezed from the heel?</p>
<p>Quite a bit.</p>
<p>Erica Twiggs is a phlebotomist at University Hospitals, a specialist in drawing blood. She’s explaining to mother Tiffany Cone of Bedford, Ohio that she’s taking her baby to the nursery for newborn screening.</p>
<p>&#8220;She’s sleeping so peacefully … let’s see how long this is going to last,&#8221; Twiggs said.</p>
<p>Twiggs readies the needle and quickly pricks the heel of Cone’s baby, Kennedy.</p>
<p>Kennedy is no longer fuzzy with sleep.</p>
<p>&#8220;Almost done, honey,&#8221; Twiggs said.</p>
<p>Blood from baby Kennedy’s heel hits the absorbent paper of the official Ohio newborn screening form.</p>
<p>Five perfect circles of bright red blood stand out against the form’s white background. In a couple minutes, Twiggs is finished and the sample is ready to send off for testing.</p>
<p>Chances are, baby Kennedy is just fine, but some babies do have genetic disorders that, when caught early, can be treated.</p>
<p>Marsha Bigham remembers the needle stick &#8220;like it was yesterday.&#8221;</p>
<p>Marsha Bigham and her 19-year-old son Josh are from Canal Fulton, just south of Akron.</p>
<p>When Josh was born, the blood from his heel stick showed he has a condition called Phenylketonuria, or PKU.</p>
<p>&#8220;We knew nothing about PKU&#8221; Marsha Bigham said.</p>
<p>But they learned quickly. Within a week of birth, Josh was put on a special diet by his doctors at Akron Children’s Hospital. People with PKU can’t break down proteins and if they breast feed or later eat meat &amp; dairy, it can cause irreversible brain damage.</p>
<p>PKU is pretty rare—about one in every twenty five thousand babies is born with it in the US.</p>
<p>In Josh’s case the early intervention was a success.</p>
<p>He’s a full time student and a natural with cars. It takes him a while to think of a auto repair that actually challenges him:</p>
<p>Josh is a typical teenager&#8211;dirt bikes, girlfriend, short answers—and this is because of newborn screening.</p>
<p>His mom gets quiet when she thinks of what might’ve happened without it.</p>
<p>&#8220;I mean he would have been severely mentally challenged,&#8221; Marsha Bigham said.</p>
<p>PKU is the flagship disease for newborn screening. It kick-started the practice in the sixties, and now most states screen for a core group of about 30 different disorders.</p>
<p>Here’s how it works: those drops of blood from the heel stick contain information about a person’s genes and how they process nutrients. Clues in the blood can send up red flags, and alert doctors to certain disorders, like PKU, sickle cell anemia and cystic fibrosis.</p>
<p>The Ohio Department of Health runs the state’s Newborn Screening Program, and Sharon Linard is a supervisor there. She says blood is a window to the body.</p>
<p>It’s very easy to get and it has a ton of information in it,&#8221; Linard said.</p>
<p>After a heel stick, all those samples are over-nighted to the Department of Health’s lab in Columbus. Results are usually known within 24 hours and they’re faxed or phoned in to the baby’s doctor’s office. In a given year, they identify an average of 250 babies in Ohio with genetic disorders.</p>
<p>Ohio screens for nearly all of the core diseases recommended by federal guidelines. These are conditions that benefit from early detection.</p>
<p>&#8220;If we don’t have a treatment, we will not test for it,&#8221; Linard said.</p>
<p>Linard says the most common disorder that crops up in Ohio is hypothyroidism, where the baby doesn’t have enough thyroid hormone to keep growing, and the fix is simple: take a pill. Other common ones are sickle cell and cystic fibrosis. More rare disorders, like something called Maple Syrup Urine Disease, might surface only once in a blue moon.</p>
<p>The Centers for Disease Control and Prevention call newborn screening one of the ten greatest public health achievements in the U.S. over the last decade. It’s estimated that over five thousand of the 4 million babies born in the states each year will have one of the conditions that’s screened for.</p>
<p>&#8220;When you think about the babies you save by this, these are babies who have normal lives and wouldn’t have had normal lives otherwise,&#8221; Linard said.</p>
<p>All thanks to a couple drops of blood.</p>
]]></content:encoded>
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			<itunes:keywords>blood,disease,disorder,doctors,genetic,public health,treatment</itunes:keywords>
	<itunes:subtitle>There’s one thing all Americans share at birth. It&#039;s the experience of having a heel stick, a jab that draws blood used for all types of screening. How much can doctors learn from a few drops of blood squeezed from the heel?</itunes:subtitle>
		<itunes:summary>There’s one thing all Americans share at birth. It&#039;s the experience of having a heel stick, a jab that draws blood used for all types of screening. How much can doctors learn from a few drops of blood squeezed from the heel?</itunes:summary>
		<itunes:author>WOSU News</itunes:author>
		<itunes:explicit>no</itunes:explicit>
		<itunes:duration>3:57</itunes:duration>
	</item>
		<item>
		<title>A Corn with Eight New Genes &#8211; Safe?</title>
		<link>http://wosu.org/2012/news/2009/08/12/a-corn-with-eight-new-genes-safe/</link>
		<comments>http://wosu.org/2012/news/2009/08/12/a-corn-with-eight-new-genes-safe/#comments</comments>
		<pubDate>Wed, 12 Aug 2009 00:00:00 +0000</pubDate>
		<dc:creator>David Lukofsky</dc:creator>
				<category><![CDATA[Uncategorized]]></category>
		<category><![CDATA[corn]]></category>
		<category><![CDATA[genetic]]></category>
		<category><![CDATA[gmo]]></category>

		<guid isPermaLink="false">http://wosu.org/2012/news/2009/08/12/a-corn-with-eight-new-genes-safe/</guid>
		<description><![CDATA[About three quarters of corn growers in Ohio harvest genetically modified corn. Growers tend to like this type of crop because it requires less pesticide. Now, that number might increase further. The EPA just approved a new type of corn that Monsanto calls  a game-changing technology'.]]></description>
				<content:encoded><![CDATA[<p>The Environmental Protection Agency approved a new type of genetically modified corn this month called SmartStax&#8217;. The new corn &#8211; from Monsanto and Dow AgroSciences &#8211; was genetically engineered to include eight new genes in its genome. Six genes to produce pesticide, two genes to resist herbicide.</p>
<p>It&#8217;s the first time the EPA approves an eight-gene corn. In the past, the EPA approved genetically modified corn with only two extra genes, three at most.</p>
<p>But some people think the EPA has been too quick with the approval. Policy analyst Bill Freese at the Center for Food Safety in Washington worries the corn will spur the evolution of superbugs &#8211; insects resistant to conventional pesticides.</p>
<p>&#8220;First of all the EPAs decision on these crops is based almost exclusively on studies that are done by the companies that are applying for approval of the crops and that has given rise to bias,&#8221; says Freese. </p>
<p>BT is a pathogen found naturally in soil. It&#8217;s toxic to many insects, and so it&#8217;s been used as a spray-on pesticide for years.</p>
<p>Genetically modified corn like SmartStax is engineered to include the BT gene in its genome. As it grows, the corn plant produces its own dose of BT pesticide.</p>
<p>The concern is some insects in a population of Root Worm, for example, are naturally more resistant to BT. Freese says the genetically strong insects that survive could mate &#8212; producing offspring with even more resistance to BT. </p>
<p>&#8220;There&#8217;s a great concern among organic farmers that development of resistance could make BT sprays useless,&#8221; says Freese.</p>
<p>The EPA says the chances of this happening are low because it mandates growers to use a refuge&#8217;. Mike Mendelson from the EPA explains a refuge is a portion of land growers devote to non-BT corn. </p>
<p>&#8220;If resistance were to develop to the BT-corn the refuge provides non-resistant insects that could dilute that potential resistance,&#8221; says Mendelson.</p>
<p>But that&#8217;s true only if the refuge is big enough. The concern with SmartStax is that it isn&#8217;t.</p>
<p>In the past, growers had to devote 20% of their field for the refuge. With SmartStax however, the EPA reduced the requirement to 5%. Freese says it was an unwise decision for the EPA to reduce the requirement.</p>
<p>&#8220;Obviously I think we need to take an independent study with a greater seriousness than one completed by a self interested company,&#8221; says Freese.</p>
<p>Professor of Crop Sciences at Ohio State, John Finer is one of those who stand behind the SmartStax science. Finer says it&#8217;s because SmartStax combines &#8211; or stacks&#8217; &#8211; many pesticide genes into one plant.</p>
<p>&#8220;What we see in the laboratory is a &#8220;Yes, you can have insects that eventually develop a resistance&#8221;. As you stack starting more genes, the numbers get incredibly low, infinitesimally small,&#8221; says Finer.</p>
<p>Even if 5% were large enough for a refuge, Freese says he&#8217;s also concerned about grower compliance.</p>
<p> The enforcement of these refuge requirements is left to the industry and often enough these refuge requirements aren&#8217;t followed,&#8217; says Freese.</p>
<p>A consortium of companies including Monsanto and Dowe says grower compliance is about 90%. Monsanto&#8217;s Joanne Carden says the company arrived at that number by sending an online survey to its growers and by on-site assessments. </p>
<p> Growers are randomly selected, and it&#8217;s a face to face interview. We could look at invoices to see if they have properly purchased refuge seeds, and all that type of information&#8217;, says Carden.</p>
<p>Monsanto &#8211; citing anti-trust measures &#8211; won&#8217;t say how many assessments are completed each year. </p>
<p>&#8220;All I can say at this point is that it&#8217;s statistically significant for that particular growing years,&#8217; says Carden.</p>
<p>Danita Murray from the National Corn Growers Association says her association welcomes the EPA&#8217;s approval. Murray says the technology could boost a grower&#8217;s bottom line. </p>
<p>But ultimately, it&#8217;s up to growers to decide whether they&#8217;ll harvest the new genetically engineered corn.</p>
<p> I simply can&#8217;t predict, obviously that&#8217;s an individual decision each grower will make for themselves based on their own operation,&#8217; says Murray.</p>
]]></content:encoded>
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			<itunes:keywords>corn,genetic,gmo</itunes:keywords>
	<itunes:subtitle>About three quarters of corn growers in Ohio harvest genetically modified corn. Growers tend to like this type of crop because it requires less pesticide. Now, that number might increase further. The EPA just approved a new type of corn that Monsanto c...</itunes:subtitle>
		<itunes:summary>About three quarters of corn growers in Ohio harvest genetically modified corn. Growers tend to like this type of crop because it requires less pesticide. Now, that number might increase further. The EPA just approved a new type of corn that Monsanto calls  a game-changing technology&#039;.</itunes:summary>
		<itunes:author>WOSU News</itunes:author>
		<itunes:explicit>no</itunes:explicit>
		<itunes:duration>4:20</itunes:duration>
	</item>
		<item>
		<title>Puppy mills breed dogs with disorders</title>
		<link>http://wosu.org/2012/news/2007/12/12/puppy-mills-breed-dogs-with-disorders/</link>
		<comments>http://wosu.org/2012/news/2007/12/12/puppy-mills-breed-dogs-with-disorders/#comments</comments>
		<pubDate>Wed, 12 Dec 2007 00:00:00 +0000</pubDate>
		<dc:creator>Jo Ingles</dc:creator>
				<category><![CDATA[Uncategorized]]></category>
		<category><![CDATA[genetic]]></category>
		<category><![CDATA[puppy]]></category>

		<guid isPermaLink="false">http://wosu.org/2012/news/2007/12/12/puppy-mills-breed-dogs-with-disorders/</guid>
		<description><![CDATA[Ohio continues to be home to large scale operations that breed puppies under poor conditions in dirty and unsafe environments. Some puppy mills, as they are commonly called, have been shut down this year. But some state lawmakers say there are many more of these facilities that need to be shut down. These lawmakers continue to push legislation that would increase penalties for puppy mill owners and operators.]]></description>
				<content:encoded><![CDATA[<p>Ohio continues to be home to large scale operations that breed puppies under poor conditions in dirty and unsafe environments. Some puppy mills, as they are commonly called, have been shut down this year. But some state lawmakers say there are many more of these facilities that need to be shut down. These lawmakers continue to push legislation that would increase penalties for puppy mill owners and operators.</p>
]]></content:encoded>
			<wfw:commentRss>http://wosu.org/2012/news/2007/12/12/puppy-mills-breed-dogs-with-disorders/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
<enclosure url="http://wosu.org/2012/news/files/pi-import/audio/657915.mp3" length="3443566" type="audio/mpeg" />
			<itunes:keywords>genetic,puppy</itunes:keywords>
	<itunes:subtitle>Ohio continues to be home to large scale operations that breed puppies under poor conditions in dirty and unsafe environments. Some puppy mills, as they are commonly called, have been shut down this year. But some state lawmakers say there are many mor...</itunes:subtitle>
		<itunes:summary>Ohio continues to be home to large scale operations that breed puppies under poor conditions in dirty and unsafe environments. Some puppy mills, as they are commonly called, have been shut down this year. But some state lawmakers say there are many more of these facilities that need to be shut down. These lawmakers continue to push legislation that would increase penalties for puppy mill owners and operators.</itunes:summary>
		<itunes:author>WOSU News</itunes:author>
		<itunes:explicit>no</itunes:explicit>
		<itunes:duration>3:35</itunes:duration>
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